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璐ㄨ氨娴佸紡浜у搧鎸佺画璧板己锛屽瘜椴佽揪(Fluidigm) Q2鏀跺叆澧為暱7锛?/h2>

瀹為獙瀹よ祫璁綉鏃堕棿:2019-08-08 鐐瑰嚮: 娆?/span> 鐧惧害鎼滅储

銆愬璇汇€?/strong>瀵岄瞾杈綟luidigm鍛ㄥ洓鍦ㄥ競鍦烘敹鐩樺悗鎶ュ憡鍏剁浜屽搴︽敹鍏ュ悓姣斿闀?锛咃紝鍥犲叾 璐ㄨ氨娴佸紡缁嗚優浠骇鍝佺粍鍚堟寔缁蛋寮?銆?灏界鏀跺叆澧炲姞锛屼絾甯傚満鍙嶅簲娑堟瀬锛屽洜涓篎luidigm閿欒繃浜嗘渶楂樹及鍊硷紝骞朵负寰祦浣撲骇鍝侀攢鍞殑鎸佺画鐤茶蒋鎻愪緵浜嗙涓夊搴︾殑鐤茶蒋鎸囧紩銆傚湪绾虫柉杈惧厠浜ゆ槗鎵€鍛ㄤ簲涓婂崍锛孎luidigm鐨勮偂浠蜂笅璺岀害38锛呰嚦7.52缇庡厓銆?鎴嚦......
TAG鏍囩锛?璐ㄨ氨娴佸紡 瀵岄瞾杈?/a> Fluidigm Q2鏀跺叆

瀵岄瞾杈綟luidigm鍛ㄥ洓鍦ㄥ競鍦烘敹鐩樺悗鎶ュ憡鍏剁浜屽搴︽敹鍏ュ悓姣斿闀?锛咃紝鍥犲叾璐ㄨ氨娴佸紡缁嗚優浠骇鍝佺粍鍚堟寔缁蛋寮?/span>銆?/span>

灏界鏀跺叆澧炲姞锛屼絾甯傚満鍙嶅簲娑堟瀬锛屽洜涓篎luidigm閿欒繃浜嗘渶楂樹及鍊硷紝骞朵负寰祦浣撲骇鍝侀攢鍞殑鎸佺画鐤茶蒋鎻愪緵浜嗙涓夊搴︾殑鐤茶蒋鎸囧紩銆傚湪绾虫柉杈惧厠浜ゆ槗鎵€鍛ㄤ簲涓婂崍锛孎luidigm鐨勮偂浠蜂笅璺岀害38锛呰嚦7.52缇庡厓銆?span style="margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important; text-indent: 2em;">鎴嚦2019骞?鏈?0鏃ョ殑涓変釜鏈堬紝Fluidigm鎶ュ憡鐨勬敹鍏ヤ负2820涓囩編鍏冿紝鑰屽幓骞村悓鏈熶负2640涓囩編鍏冦€傚垎鏋愬笀骞冲潎棰勬湡鏀跺叆涓?060涓囩編鍏冦€備华鍣ㄦ敹鍏ヤ粠1040涓囩編鍏冮鍗?7锛呰嚦1220涓囩編鍏冿紝鑰屾秷璐瑰搧鏀跺叆鍚屾瘮涓嬮檷4锛呰嚦1,100涓囩編鍏?140涓囩編鍏冦€傛湇鍔℃敹鍏ヤ粠470涓囩編鍏冨闀?锛呰嚦500涓囩編鍏冦€?/span>

Fluidigm琛ㄧず锛岀敱浜庝华鍣ㄥ拰娑堣€楀搧鐨勯攢鍞澧炲姞锛屽ぇ瑙勬ā缁嗚優璁℃暟鏀跺叆浠庡幓骞村悓鏈熺殑1370涓囩編鍏冨闀夸簡28锛咃紝杈惧埌1750涓囩編鍏冦€備笉杩囷紝鐢变簬浠櫒鍜屾秷鑰楀搧鐨勯攢鍞涓嬮檷锛屽井娴佷綋鐨勬敹鍏ヤ粠1280涓囩編鍏冧笅闄?6锛呰嚦1070涓囩編鍏冦€?/p>

璐ㄨ氨娴佸紡浜у搧鎸佺画璧板己锛屽瘜椴佽揪(Fluidigm) Q2鏀跺叆澧為暱7锛? _width=

鍊煎緱娉ㄦ剰鐨勬槸锛孎luidigm鍦ㄧ編娲茬殑鎬讳綋閿€鍞鍚屾瘮涓嬮檷11锛呰嚦1110涓囩編鍏冿紝鑰孍MEA鍜屼簹澶湴鍖虹殑閿€鍞鍒嗗埆澧為暱浜?0锛呭拰21锛呫€傚湪涓€娆¤璁哄叕鍙镐笟缁╃殑鐢佃瘽浼氳涓婏紝Fluidigm鎬昏鍏奸甯墽琛屽畼Chris Linthwaite琛ㄧず锛岀敱浜庡叕鍙哥鐞嗗眰涓€鐩村皢娉ㄦ剰鍔涘拰绮惧姏闆嗕腑鍦ㄧ編娲插湴鍖猴紝鍏徃瀵规琛ㄧ幇鎰熷埌“鎯婅鍜屽け鏈?rdquo;銆?span style="margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important; text-indent: 2em;">Linthwaite璇达細“鍏抽敭鐨勯棶棰樻槸鎴戜滑娌℃湁鐪嬪埌缁撴瀯闂锛屽井娴佷綋鏄竴涓彈鍒版寫鎴樼殑棰嗗煙锛屼竴浜涜川閲忕粏鑳炶鏁扮郴缁熸帹杩熷埌浠婂勾涓嬪崐骞达紝鍏朵腑涓€浜涗笌璧勯噾寤惰繜鏈夊叧锛屼絾杩欎釜婕忔枟鎬讳綋涓婇潪甯告繁銆傛垜浠殑寰祦浣撲笟鍔″緢寮便€備絾鏄┍鍔ㄥ洜绱犲苟涓嶆柊椴溿€?rdquo;鍦ㄧ粰鎶曡祫鑰呯殑涓€浠芥姤鍛婁腑锛孭iper Jaffray鐨凚ill Quirk琛ㄧず锛?ldquo;鎶曡祫閾惰鎵胯澶ц妯$粏鑳炶鏁扮殑鎸佺画鍔涢噺鍜屾満浼氾紙灏界浣庝簬鎴戜滑鐨勪及璁★級锛屼絾寰祦浣撲笟鍔$户缁彈鍒版嫋绱€?rdquo;

Fluidigm杩樻彁渚涗簡绗笁瀛e害鐨勮蒋鎸囧锛屽苟鎸囧嚭鍏堕璁$涓夊搴︾殑鏀跺叆涓?700涓囩編鍏冭嚦3000涓囩編鍏冦€傚垎鏋愬笀骞冲潎棰勬湡绗笁瀛e害鏀跺叆涓?270涓囩編鍏冦€傛敞鎰忓埌璇ユ寚瀵兼槸“淇濆畧鐨?rdquo;锛屼絾璁よ瘑鍒拌鍏徃鍦?span style="color: rgb(255, 0, 0);">璐ㄨ氨缁嗚優璁℃暟鏂归潰鐨勬寔缁紭鍔?/strong>锛孭iper Jaffray缁存寔鍏跺Fluidigm鑲$エ鐨勫鎸佽瘎绾э紝浣嗗湪2020骞翠及璁$暐浣庣殑鎯呭喌涓嬪皢鍏朵环鏍肩洰鏍囦笅璋冭嚦15缇庡厓銆?/p>

Linthwaite鍦ㄨ储鎶ョ數璇濅細璁笂鎸囧嚭锛岃鍏徃鏈€杩戝湪缇庢床澶ч噺閲囩敤鏂颁骇鍝佸拰鐩稿叧娑堣€楀搧銆?ldquo;鎴戜滑鐩镐俊鎴戜滑鐨?strong>澶ц妯$粏鑳炶閲忔秷鑰楀搧閿€鍞湁鏈涘姞閫燂紝鎴戜滑璁や负缇庢床灏嗘槸涓€涓緢澶х殑涓嬪崐骞达紝鍦ㄧ鍥涘搴﹀皢鏈変竴涓噸澶ц繘姝ャ€?rdquo;

鍦ㄦ湰瀛e害锛孎luidigm鎺ㄥ嚭浜嗚澶氭柊鐨勫ぇ瑙勬ā缁嗚優璁℃暟浜у搧锛屽寘鎷?5绉嶇敤浜庢垚鍍忚川璋辩殑鏂版姉浣?鐢ㄤ簬鍏嶇柅鑲跨槫瀛︾爺绌剁殑涓夌鏂板瀷鎴愬儚璐ㄨ氨娴佸紡缁嗚優浠瘯鍓傜洅; CyTOF杞欢绠€鍖栦簡澶ц妯$粏鑳炶鏁拌浇鐜荤墖鍜岀洰鍓嶅熀浜?strong>CyTOF鐨勭粏鑳炲垎鏋?/span>鐨勪竷绉嶆柊閲戝睘鐨勯€夋嫨鍜岃幏鍙栨劅鍏磋叮鍖哄煙銆?/p>

姝ゅ锛岃鍏徃杩樻帹鍑轰簡涓ょ鍩哄洜缁勫妫€娴?/strong>鏂规硶锛岄€氳繃鍏跺井娴佷綋閮ㄩ棬杩涜閿€鍞細Advanta RNA Fusions鍜孲olid Tumor NGS Library Prep妫€娴嬨€傝鍏徃浠婂ぉ杩樿〃绀哄皢鍦ㄧ涓夊搴︿负鍏禞uno寰祦浣撶郴缁熷紩鍏ヨ嚜鍔ㄥ寲RNA娴嬪簭鏂囧簱鍒跺宸ヤ綔娴佺▼銆?/p>

鍏充簬鍗冲皢鎺ㄥ嚭鐨?span style="color: rgb(255, 0, 0);">RNA-seq鏂囧簱鍒跺浜у搧锛孡inthwaite鍦ㄧ數璇濅細璁腑鎸囧嚭锛屽競鍦虹爺绌惰〃鏄庢暣浣揜NA-seq甯傚満浠峰€艰秴杩?2浜跨編鍏冿紝姣忓勾澧為暱15锛呫€傝鍏徃浼拌锛孯NA-seq鍓嶇殑鏂囧簱鍒跺浠h〃浜?浜跨編鍏冪殑甯傚満銆?span style="margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important; text-indent: 2em;">Linthwaite璇达細“甯傚満鍒嗘暎锛屾病鏈夌珵浜夊鎵嬪皢鑷姩鍖栧钩鍙颁笌璇曞墏鐩哥粨鍚堬紝鐢ㄤ簬闆嗘垚瑙e喅鏂规锛岃瘯鍓傛垚鏈拰闀挎椂闂寸殑鎿嶄綔鏃堕棿瑕佹眰娑堣€楀洓鍒颁簲涓皬鏃剁殑鐮旂┒浜哄憳銆侳luidigm鐨勮嚜鍔ㄥ井娴佷綋瑙e喅鏂规鍙互鎻愪緵鏄剧潃鐨勬垚鏈紭鍔?- 鍙兘姣斿叾浠栦骇鍝佷究瀹滀袱鍒颁笁鍊嶏紝闄嶄綆浜嗘瘡涓牱鍝佺殑鎴愭湰骞堕噴鏀炬洿澶氭帓搴忕殑娼滃姏锛屼粠鑰屾彁楂樺悶鍚愰噺銆?rdquo;

Fluidigm鐨勭浜屽搴﹀噣浜忔崯涓?380涓囩編鍏冿紝鍗虫瘡鑲?.2缇庡厓锛岃€屽幓骞村悓鏈熶负1620涓囩編鍏冿紝鍗虫瘡鑲?.42缇庡厓銆侳luidigm浣跨敤浜嗗ぇ绾?900涓囪偂鏉ヨ绠楁渶杩戝畬鎴愮殑瀛e害姣忚偂浜忔崯锛岀浉姣斾箣涓嬶紝2018骞寸浜屽搴︾殑姣忚偂浜忔崯绾︿负3900涓囪偂銆?/span>

锛堟湰鏂囨潵婧愶細浠櫒缁忕悊浜?鍒樼珛涓? 锛?

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TAG鏍囩锛?璐ㄨ氨娴佸紡 瀵岄瞾杈?/a> Fluidigm Q2鏀跺叆
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